As we near the 2nd anniversary of the SALK Institute spike protein findings... How "Following the Scientific Method" works

Shame on science advisors for being unaware of leading edge COVID-19 research from TWO years ago - KEY developments KNOWN March - August 2021.

Feb 15, 2023

Following the Science – A simple introduction to the Scientific Method illustrated by key COVID-19 related research findings of 2020 & 2021 (Reposted from https://r.8b.io/387157/assets/files/Part_B_intro_and_5_9.pdf for easier reference!)

Science does not stand still. New observations and new questions lead to new hypotheses and, ultimately, new conclusions, which in turn lead to new observations, etc.

Image: https://thebiologyprimer.com/introduction-to-the-scientific-method/

AN EXAMPLE of the OBSERVATION/QUESTION/HYPOTHESIS Phases

First case of postmortem study in a patient vaccinated against SARS-CoV-2

(Source) https://www.sciencedirect.com/science/article/pii/S1201971221003647.

Healthy 86-year-old was given his first shot of Pfizer BioNtech vaccine and ended up with kidney failure. In hospital, he picked up a Covid infection from another patient. At his death the autopsy revealed mRNA throughout his body....

Possible reasons...

The lipid nanoparticles in the vaccine deliver mRNA around the body, which could mean spike protein production in every organ would have been the next step if he had not died.
OR
The vaccination accelerated the replication of the virus in the body (known as ADE or Antibody Dependent Enhancement) such that the infection the man got in hospital could have spread much faster than would normally be the case without vaccination.

For more observations on autopsies of post-vaccination deaths, see Cole, Ryan, MD. Covid-19 vaccines and autopsy results. Video presentation. White Coat Summit, August 3, 2021. https://rumble.com/vkoz3c-summit-sessions-the-science-ryan-cole-md-covid-19-vaccines-and-autopsy.html. Already in March 2021, in order to better study (or rule out) a causative correlation between COVID-19 vaccinations, inflammation and death, professional organizations of pathologists in Germany have written the German health minister to mandate autopsies in cases of sudden death inside and outside of the clinical setting, but received no response. Given that the American VAERS reporting system has been assessed at only reporting 1% of all cases (i.e. with 99% of all vaccine injuries and deaths going unreported, attributed to other causes) the director of the Institute of Pathology at the University of Heidelberg, Dr. Peter Schirmacher is one of many to push for more autopsies in order to arrive at a more nuanced risk/benefit analysis of these vaccines. See https://anthraxvaccine.blogspot.com/2021/09/german-pathologist-sounds-alarm-on.html or https://corona-blog.net/2021/08/03/peter-schirmacher-der-chef-pathologe-der-uni-heidelberg-fordert- deutliche-mehr-obduktionen-von-geimpften/ (in German) as well as the statement of position dated March 22, 2021 https://link.springer.com/content/pdf/10.1007/s00292-021-00959-0.pdf.

AN EXAMPLE of the QUESTION/HYPOTHESIS/EXPERIMENT/ANALYSIS Phases

An excerpt from Corona Unmasked – New Facts and Figures (prepublication chapter, 2021) by Dr. Sucharit Bhakdi, retired Thai-German medical microbiologist, former head of the Institute of Medical Microbiology and Hygiene at the University of Mainz, Germany. Written In collaboration with molecular biologist Professor Karina Reiss. https://www.goldegg-verlag.com/goldegg-verlag/wp-content/uploads/corona_unmasked_engl_leseprobe.pdf

This text was based on the authors’ prior experience, knowledge of previous attempts and unanswered questions, as well as the little preliminary data available from the clinical trails of the various vaccine manufacturers at the time.

And now back to the new reality: the large-scale experiment on humans. The injected gene packets are taken up locally in muscle cells, but a large part reaches first the local lymph nodes and, after passing through these, the bloodstream. The lymph nodes are where the immune cell team resides.

The authors’ prior observations lead them to question and hypothesize.

When the viral gene is taken up by any cell there, production of the spike protein gets underway. The corona killer lymphocyte next door wakes up and springs into action – the brotherly battle begins! Lymph node swelling. Pain. The lymphocytes psyche each other up and then emerge from the lymph nodes to seek out more enemies.
Yes – over there – the muscle cells! There they are!!! Attack!!! At the injection site redness, swelling, bad pain.
But now the nightmare.

Then as data comes out, either through the clinical trials or other scientific studies, the observations are analyzed and new questions are asked and hypotheses made.

This is because the substances with small molecules – for example, blood sugar – can easily seep out of the blood into the tissue, whereas large molecules such as proteins cannot. For them, the vessel walls are tight thanks to the lining with a cell layer – the endothelial cells.
What are the gene packages like – large or small?
Right – compared to blood sugar, they certainly are large. Therefore, once they enter the bloodstream, they will remain in the closed network of vascular tubes just like the blood cells. A small part of them is taken up by white blood cells. Presumably, however, most of the virus factories will be established in the endothelial cells, that is, in the innermost cell layer of the blood vessels themselves. This would happen mainly where the blood flows slowly – within the smallest vessels – because the gene packages can be taken up particularly efficiently by the cells there.
The endothelial cells then produce the viral spike protein and place the waste at the door – on the side that faces the bloodstream, where killer lymphocytes are on patrol. This time, the fight is one-sided. The endothelial cells have no defense.
What happens then can only be guessed at. Injury to the vascular lining usually leads to the formation of blood clots. This would likely happen in countless vessels in countless places in the body. If it happens in the placenta, severe damage to the child in the womb could result.
Shudder.

Connecting new observations with previous background knowledge.

Is there evidence that something like this is taking place? Yes, there is talk of rare blood disorders in which a possible link to vaccination would have to be investigated (31). Strikingly, there are reports of patients in whom a sharp drop in blood platelets (thrombocytes) was observed. This would fit the hypothesis put forward here, because platelets are activated and used up at the sites of blood clot formation.

Considering ways in which to test out a new hypothesis, i.e. testing for D-Dimers in the blood before and after vaccination; examining autopsies once available; considering the preventative use of blood thinners, prior to receiving the vaccine, as a possible precaution, ...

Could you check if the assumption is correct? Yes. Laboratory findings provide immediate information on whether blood clotting is underway. Autopsies could clarify whether clots have formed in the small vessels. And in the meantime, consideration could be given to whether anticoagulants should be administered to patients as a preventive measure. The administration of cortisone preparations to dampen lymphocyte activity might also be worth considering.

Now these hypotheses could be addressed specifically in new experiments.

2 Pivotal Studies from Early 2021 (SALK institute & Japan)

Because the mRNA in the COVID-19 vaccine products instructs the body to produce the spike protein component of the Corona virus in order to mount an immune response, researchers noted with interest two studies published early in 2021, showing that the spike protein component of the SARS Cov-2 virus WITHOUT the rest of the virus can cause cell tissue damage. Magro, et. al examined spike protein in the context of COVID-19 infections and its associated lung damage. (February, 2021) https://www.sciencedirect.com/science/article/abs/pii/S109291342030191X. On March 31, 2021, the American Salk Institute published results showing that exposure to a “pseudovirus” that contained SARS-CoV-2 spike proteins, but did not contain any actual virus, resulted in damage to the lungs and arteries of animal models. Tissue samples showed inflammation in endothelial cells lining the pulmonary artery walls. “The novel coronavirus’ spike protein plays additional key role in illness”https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.121.318902 + https://www.salk.edu/news-release/the-novel-coronavirus-spike-protein-plays-additional-key- role-in-illness/. Various voices were quick to insist that this finding could not apply to vaccine- induced spike protein production, which then of course, gave rise to the circle of observation, question, hypothesis, experimentation yet again.

As well, the biodistribution data from Pfizer, made available to the Japanese regulators, further propels this ongoing cycle of observing, questioning, hypothesizing, experimenting etc. among those following the science worldwide.

This biodistribution data reflected the speed at which the lipid nanoparticles spread from the injection site all around the body within 48 hours using an animal model (rat). Lipid nanoparticles encase the mRNA which is to instruct the body’s cells to make spike protein. The presence of this spike protein should then train the body’s immune system to fight.

Lipid nanoparticle “vehicles” to “transport” the mRNA was a mechanism recently tested in cancer research and now applied to COVID-19. The data was provided to Japan (in Japanese) and Canadian immunologist and vaccine researcher Dr. Byram Bridle, along with the Pandemic Data & Analytics Institute (PANDA) were instrumental in making it available in English.

To hear Dr. Bridle discuss the surprising levels of post-vaccination lipid concentration in the various organs in such a short time frame, see: https://omny.fm/shows/on-point-with-alex- pierson/dr-byram-bridle-on-point-with-alex-pierson

https://www.pmda.go.jp/drugs/2021/P20210212001/672212000_30300AMX00231_I100_1.pd f#page=16

Learning from VAERS data

Currently based in Israel, Canadian born Dr. Jessica Rose has been analyzing the data posted on the USA based VAERS reporting system for vaccine injuries. Using her wide-ranging background in applied mathematics, immunology, medicine, and molecular and computational biology she builds on the hypotheses and study data shown above to look at real-world human vaccination data. Her analysis, with supporting presentation slides addresses the extent to which causality can be established, the issues of underreporting and many other questions. See https://covexit.com/vaers-what-do-the-data-tell-us/

Learning about blood clotting, D-Dimer testing & complications

Seeking a way to confirm the hypothesis whether vaccination can lead to spike protein induced blood clotting, Dr. Bhakdi refers to a recently published study showing that 30-40% of those who were tested for D-Dimer production before and after their first vaccination showed the presence of D-Dimers which means that they will have developed some degree of microscopic blood clotting. Dr. Charles Hoffe reports even higher rates.https://www.bitchute.com/hashtag/sucharit-bhakdi/ A D-Dimer test measures a substance that is released when a blood clot breaks up. https://myhealth.alberta.ca/health/Pages/conditions.aspx?hwid=abn2838

Here is a more recent interview with Dr. Sukharit Bhakdi with an update on the research around these processes https://www.globalresearch.ca/microbiologist-explains-covid-jab- effects/5753710

Given that the substance is not present when there are no blood clotting issues, various physicians and researchers hypothesize that this can be a straightforward way to ensure that those who do indeed have micro-clotting issues post-vaccination receive anti-coagulant medication as soon as possible to avoid potential clotting related adverse events, such as strokes, heart attacks, paralysis, organ damage, etc.

A screen capture from https://www.bitchute.com/hashtag/sucharit-bhakdi/ showing the inside walls of a blood vessel. The short lines represent spike proteins created by cells along the walls. The lymphocytes, aka Killer T-cells, will attempt to not only capture the foreign spike proteins but also the cells thatproduced them. The ensuing “battle” is highly likely to result in free-flowing fragments, around which blood platelets will likely gather, starting clot formation. Even miniscule clots have the potential to become larger over time, resulting in stroke like blockage of blood vessels further downstream. This can lead to tissue asphyxiation, disabilities or death.

AN EXAMPLE of the OBSERVATION EXPERIMENT, ANALYSIS & CONCLUSION Phases

but also an example of:

Treatment of COVID-19 information suppressed to allow for Pharma Emergency Use Authorization

“Untreated SARS-COV 2 progresses in three distinct stages with the virus replicating quickly early on. Providing treatment early is the key to preventing hospitalization and death.” Dr. Peter McCullough can be heard explaining this at the event filmed below:

Treatment Stages (for Covid-19) https://hcqmeta.com/#results (Figure 2)

Since the first publication by Peter A. McCullough, M.D., M.P.H., (FORMER) Vice Chief of Internal Medicine, Baylor University Medical Center, et al. entitled "Pathophysiological Basis and Rationale for Early Outpatient Treatment of SARS-CoV-2 (COVID-19) Infection." in the American Journal of Medicine, August 2020, a number of other successful treatment protocols have been identified for the Four Treatment Stages that correspond with the progression of Covid-19 in the body. (See https://www.canadiancovidcarealliance.org/treatment-protocols/ or listen to Dr. Richard Urso https://thewhistleblowernewsroom.podbean.com/ - episode from 04.30.21)

COVID-19 early treatment: real-time analysis of 975 studies. https://c19early.org

This website tracks recent studies and international adoption of the following therapeutics to be used as early treatments for COVID-19 and includes:

Aspirin Bamlanivimab Bromhexine Budesonide Casirivimab/i.. Colchicine Conv.Plasma Curcumi n Favipiravir Fluvoxamine Hydroxychloro.. Iota-
carragee. Ivermectin Melatonin Molnupiravir NigellaSativa Nitazoxanide Povidone-
Iod. Probiotics Proxalutamide Quercetin Remdesivir Sotrovimab Vitamin A Vitamin C Vitamin D Zinc

Treatments do not replace vaccines and other measures. All practical, effective, and safe means should be used. Elimination is a race against viral evolution. No treatment, vaccine, or intervention is 100% available and effective for all variants. Denying efficacy increases the risk of COVID-19 becoming endemic; and increases mortality, morbidity, and collateral damage.

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